Lantz, Kristen A

Inhibition of PTP1B by trodusquemine (MSI-1436) causes fat-specific weight loss in diet-induced obese mice. [electronic resource] - Obesity (Silver Spring, Md.) Aug 2010 - 1516-23 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1930-739X

10.1038/oby.2009.444 doi


Animals
Appetite--drug effects
Body Composition--drug effects
Cholestanes--pharmacology
Diet
Disease Models, Animal
Hep G2 Cells
Humans
Hypolipidemic Agents--pharmacology
Hypothalamus--drug effects
Insulin--blood
Leptin--blood
Male
Mice
Mice, Inbred AKR
Mice, Obese
Obesity--drug therapy
Phosphorylation
Protein Tyrosine Phosphatase, Non-Receptor Type 1--antagonists & inhibitors
Receptor, Insulin--metabolism
STAT3 Transcription Factor--metabolism
Spermine--analogs & derivatives
Weight Loss--drug effects