TY - GEN AU - Jin,Sheng-Yu AU - Skipwith,Christopher G AU - Zheng,X Long TI - Amino acid residues Arg(659), Arg(660), and Tyr(661) in the spacer domain of ADAMTS13 are critical for cleavage of von Willebrand factor SN - 1528-0020 PY - 2010///0413 KW - ADAM Proteins KW - chemistry KW - ADAMTS13 Protein KW - Amino Acid Sequence KW - Arginine KW - metabolism KW - Cells, Cultured KW - Humans KW - Immobilized Proteins KW - Kinetics KW - Models, Molecular KW - Molecular Sequence Data KW - Mutant Proteins KW - Peptides KW - Protein Binding KW - Protein Multimerization KW - Protein Structure, Secondary KW - Protein Structure, Tertiary KW - Recombinant Fusion Proteins KW - Rheology KW - Stress, Mechanical KW - Structure-Activity Relationship KW - Tyrosine KW - von Willebrand Factor N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1182/blood-2009-07-235101 ER -