TY  - GEN
AU  - van der Bol,Jessica M
AU  - Mathijssen,Ron H J
AU  - Creemers,Geert-Jan M
AU  - Planting,André S Th
AU  - Loos,Walter J
AU  - Wiemer,Erik A C
AU  - Friberg,Lena E
AU  - Verweij,Jaap
AU  - Sparreboom,Alex
AU  - de Jong,Floris A
TI  - A CYP3A4 phenotype-based dosing algorithm for individualized treatment of irinotecan
SN  - 1557-3265
PY  - 2010///0412
KW  - Adult
KW  - Aged
KW  - Algorithms
KW  - Antineoplastic Agents, Phytogenic
KW  - administration & dosage
KW  - Camptothecin
KW  - Carcinoma
KW  - drug therapy
KW  - Colorectal Neoplasms
KW  - Cytochrome P-450 CYP3A
KW  - genetics
KW  - Drug Dosage Calculations
KW  - Female
KW  - Humans
KW  - Individuality
KW  - Irinotecan
KW  - Male
KW  - Midazolam
KW  - Middle Aged
KW  - Models, Biological
KW  - Neoplasm Metastasis
KW  - Phenotype
KW  - Precision Medicine
KW  - methods
KW  - Prodrugs
N1  - Publication Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1158/1078-0432.CCR-09-1526
ER  -