TY - GEN AU - Hu,Wei AU - Xu,Ruijuan AU - Sun,Wei AU - Szulc,Zdzislaw M AU - Bielawski,Jacek AU - Obeid,Lina M AU - Mao,Cungui TI - Alkaline ceramidase 3 (ACER3) hydrolyzes unsaturated long-chain ceramides, and its down-regulation inhibits both cell proliferation and apoptosis SN - 1083-351X PY - 2010///0415 KW - Alkaline Ceramidase KW - genetics KW - Apoptosis KW - physiology KW - Carcinoma, Squamous Cell KW - pathology KW - Cell Division KW - Ceramidases KW - Ceramides KW - metabolism KW - Culture Media, Serum-Free KW - pharmacology KW - Cyclin-Dependent Kinase Inhibitor p21 KW - Down-Regulation KW - Endothelial Cells KW - cytology KW - Gene Expression Regulation, Enzymologic KW - HeLa Cells KW - Humans KW - Hydrolysis KW - Keratinocytes KW - Muscle, Smooth, Vascular KW - RNA, Messenger KW - RNA, Small Interfering KW - Skin Neoplasms KW - Substrate Specificity KW - Umbilical Veins N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S UR - https://doi.org/10.1074/jbc.M109.063586 ER -