Partial silencing of methyl cytosine protein binding 2 (MECP2) in mesenchymal stem cells induces senescence with an increase in damaged DNA. [electronic resource]
- FASEB journal : official publication of the Federation of American Societies for Experimental Biology May 2010
- 1593-603 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1530-6860
10.1096/fj.09-143057 doi
Cell Cycle--genetics Cells, Cultured Cellular Senescence--genetics Cytosine--metabolism DNA Damage DNA Methylation DNA Repair--genetics Down-Regulation Gene Silencing Humans Mesenchymal Stem Cells--physiology Methyl-CpG-Binding Protein 2--genetics Retinoblastoma Protein--metabolism Tumor Suppressor Protein p53--metabolism