TY  - GEN
AU  - Kim,J A
AU  - Lee,J
AU  - Margolis,R L
AU  - Fotedar,R
TI  - SP600125 suppresses Cdk1 and induces endoreplication directly from G2 phase, independent of JNK inhibition
SN  - 1476-5594
PY  - 2010///0423
KW  - Anthracenes
KW  - pharmacology
KW  - Aurora Kinases
KW  - Blotting, Western
KW  - CDC2 Protein Kinase
KW  - antagonists & inhibitors
KW  - Cell Cycle Proteins
KW  - metabolism
KW  - Cell Line, Tumor
KW  - Cyclin B
KW  - Cyclin-Dependent Kinase 2
KW  - DNA Replication
KW  - drug effects
KW  - Enzyme Activation
KW  - Flow Cytometry
KW  - G2 Phase
KW  - HCT116 Cells
KW  - Humans
KW  - JNK Mitogen-Activated Protein Kinases
KW  - Mitosis
KW  - Phosphorylation
KW  - Protein Serine-Threonine Kinases
KW  - Proto-Oncogene Proteins
KW  - RNA Interference
KW  - Tumor Suppressor Protein p53
KW  - Polo-Like Kinase 1
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural
UR  - https://doi.org/10.1038/onc.2009.464
ER  -