SRT1720, SRT2183, SRT1460, and resveratrol are not direct activators of SIRT1. [electronic resource]
- The Journal of biological chemistry Mar 2010
- 8340-51 p. digital
Publication Type: Journal Article
1083-351X
10.1074/jbc.M109.088682 doi
Acetylation--drug effects Allosteric Regulation--drug effects Animals Blood Glucose--drug effects Calorimetry Diabetes Mellitus, Type 2--drug therapy Dietary Fats--pharmacology Enzyme Activation--drug effects Enzyme Inhibitors--chemistry Heterocyclic Compounds, 4 or More Rings--chemistry Humans Mice Mice, Obese Nuclear Magnetic Resonance, Biomolecular Resveratrol Rhodamines Sirtuin 1--metabolism Stilbenes--chemistry Substrate Specificity Surface Plasmon Resonance Tumor Suppressor Protein p53--metabolism