TY - GEN AU - Bonelli,Mara A AU - Fumarola,Claudia AU - Alfieri,Roberta R AU - La Monica,Silvia AU - Cavazzoni,Andrea AU - Galetti,Maricla AU - Gatti,Rita AU - Belletti,Silvana AU - Harris,Adrian L AU - Fox,Stephen B AU - Evans,Dean B AU - Dowsett,Mitch AU - Martin,Lesley-Ann AU - Bottini,Alberto AU - Generali,Daniele AU - Petronini,Pier Giorgio TI - Synergistic activity of letrozole and sorafenib on breast cancer cells SN - 1573-7217 PY - 2011///0131 KW - Adaptor Proteins, Signal Transducing KW - metabolism KW - Antineoplastic Combined Chemotherapy Protocols KW - pharmacology KW - Apoptosis KW - drug effects KW - Apoptosis Inducing Factor KW - Aromatase KW - genetics KW - Aromatase Inhibitors KW - Benzenesulfonates KW - Breast Neoplasms KW - enzymology KW - Caspase 7 KW - Caspase 9 KW - Cell Cycle KW - Cell Cycle Proteins KW - Cell Line, Tumor KW - Cell Proliferation KW - Cyclin D1 KW - Cytochromes c KW - Dose-Response Relationship, Drug KW - Drug Resistance, Neoplasm KW - Drug Synergism KW - Estradiol KW - Female KW - Humans KW - Letrozole KW - Mechanistic Target of Rapamycin Complex 1 KW - Multiprotein Complexes KW - Niacinamide KW - analogs & derivatives KW - Nitriles KW - Phenylurea Compounds KW - Phosphoproteins KW - Phosphorylation KW - Poly (ADP-Ribose) Polymerase-1 KW - Poly(ADP-ribose) Polymerases KW - Protein Kinase Inhibitors KW - Proteins KW - Proto-Oncogene Proteins c-myc KW - Pyridines KW - Retinoblastoma Protein KW - Ribosomal Protein S6 Kinases, 70-kDa KW - Sorafenib KW - TOR Serine-Threonine Kinases KW - Testosterone KW - Time Factors KW - Transfection KW - Triazoles N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1007/s10549-009-0714-5 ER -