Kim, Hyunmi <br/><br/>
Antifibrotic effect of Pirfenidone on orbital fibroblasts of patients with thyroid-associated ophthalmopathy by decreasing TIMP-1 and collagen levels.  [electronic resource] 

 -  Investigative ophthalmology & visual science  Jun 2010 
 - 3061-6 p.  digital 
<br/><br/> Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1552-5783 
<br/><br/><label>Standard No.: </label>10.1167/iovs.09-4257  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adult<br/>Aged<br/>Anti-Inflammatory Agents, Non-Steroidal--pharmacology<br/>Blotting, Western<br/>Cell Culture Techniques<br/>Cell Survival<br/>Collagen--metabolism<br/>Dexamethasone--pharmacology<br/>Dose-Response Relationship, Drug<br/>Enzyme-Linked Immunosorbent Assay<br/>Female<br/>Fibroblasts--drug effects<br/>Graves Ophthalmopathy--metabolism<br/>Humans<br/>Hydroxyproline--metabolism<br/>Intercellular Signaling Peptides and Proteins--pharmacology<br/>Interleukin-1beta--pharmacology<br/>Male<br/>Middle Aged<br/>Orbit--drug effects<br/>Pyridones--pharmacology<br/>Tissue Inhibitor of Metalloproteinase-1--metabolism<br/>Tumor Necrosis Factor-alpha--antagonists & inhibitors<br/>Young Adult