TY  - GEN
AU  - Falasca,M
AU  - Chiozzotto,D
AU  - Godage,H Y
AU  - Mazzoletti,M
AU  - Riley,A M
AU  - Previdi,S
AU  - Potter,B V L
AU  - Broggini,M
AU  - Maffucci,T
TI  - A novel inhibitor of the PI3K/Akt pathway based on the structure of inositol 1,3,4,5,6-pentakisphosphate
SN  - 1532-1827
PY  - 2010///0209
KW  - Adenocarcinoma
KW  - drug therapy
KW  - Animals
KW  - Antineoplastic Agents
KW  - chemical synthesis
KW  - Apoptosis
KW  - drug effects
KW  - Cell Line, Tumor
KW  - Drug Delivery Systems
KW  - Drug Design
KW  - Enzyme Activation
KW  - Female
KW  - Humans
KW  - Inositol Phosphates
KW  - Intracellular Signaling Peptides and Proteins
KW  - Male
KW  - Mice
KW  - Mice, Nude
KW  - Molecular Structure
KW  - Ovarian Neoplasms
KW  - Phosphoinositide-3 Kinase Inhibitors
KW  - Prostatic Neoplasms
KW  - Protein Kinase Inhibitors
KW  - Protein Serine-Threonine Kinases
KW  - Proto-Oncogene Proteins c-akt
KW  - antagonists & inhibitors
KW  - Signal Transduction
KW  - Structure-Activity Relationship
KW  - TOR Serine-Threonine Kinases
KW  - Xenograft Model Antitumor Assays
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1038/sj.bjc.6605408
ER  -