AZD8055 is a potent, selective, and orally bioavailable ATP-competitive mammalian target of rapamycin kinase inhibitor with in vitro and in vivo antitumor activity. [electronic resource]
- Cancer research Jan 2010
- 288-98 p. digital
Publication Type: Journal Article
1538-7445
10.1158/0008-5472.CAN-09-1751 doi
Animals Antineoplastic Agents--pharmacology Cell Proliferation--drug effects Female Humans Mice Mice, Nude Morpholines--pharmacology Neoplasms, Experimental--drug therapy Protein Kinase Inhibitors--pharmacology Protein Kinases--drug effects Signal Transduction--drug effects TOR Serine-Threonine Kinases Xenograft Model Antitumor Assays