TY  - GEN
AU  - Polasek,Thomas M
AU  - Sadagopal,Janani S
AU  - Elliot,David J
AU  - Miners,John O
TI  - In vitro-in vivo extrapolation of zolpidem as a perpetrator of metabolic interactions involving CYP3A
SN  - 1432-1041
PY  - 2010///0506
KW  - Administration, Oral
KW  - Age Factors
KW  - Aged
KW  - Aged, 80 and over
KW  - Area Under Curve
KW  - Computer Simulation
KW  - Cytochrome P-450 CYP3A
KW  - metabolism
KW  - Cytochrome P-450 CYP3A Inhibitors
KW  - Cytochrome P-450 Enzyme Inhibitors
KW  - Cytochrome P-450 Enzyme System
KW  - Dose-Response Relationship, Drug
KW  - Drug Interactions
KW  - Enzyme Inhibitors
KW  - pharmacology
KW  - Female
KW  - Humans
KW  - Liver
KW  - drug effects
KW  - Male
KW  - Metabolic Clearance Rate
KW  - Microsomes, Liver
KW  - enzymology
KW  - Midazolam
KW  - administration & dosage
KW  - Models, Biological
KW  - Pyridines
KW  - Recombinant Proteins
KW  - antagonists & inhibitors
KW  - Young Adult
KW  - Zolpidem
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1007/s00228-009-0760-2
ER  -