Polasek, Thomas M <br/><br/>
In vitro-in vivo extrapolation of zolpidem as a perpetrator of metabolic interactions involving CYP3A.  [electronic resource] 

 -  European journal of clinical pharmacology  Mar 2010 
 - 275-83 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1432-1041 
<br/><br/><label>Standard No.: </label>10.1007/s00228-009-0760-2  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Administration, Oral<br/>Age Factors<br/>Aged<br/>Aged, 80 and over<br/>Area Under Curve<br/>Computer Simulation<br/>Cytochrome P-450 CYP3A--metabolism<br/>Cytochrome P-450 CYP3A Inhibitors<br/>Cytochrome P-450 Enzyme Inhibitors<br/>Cytochrome P-450 Enzyme System--metabolism<br/>Dose-Response Relationship, Drug<br/>Drug Interactions<br/>Enzyme Inhibitors--pharmacology<br/>Female<br/>Humans<br/>Liver--drug effects<br/>Male<br/>Metabolic Clearance Rate<br/>Microsomes, Liver--enzymology<br/>Midazolam--administration & dosage<br/>Models, Biological<br/>Pyridines--pharmacology<br/>Recombinant Proteins--antagonists & inhibitors<br/>Young Adult<br/>Zolpidem