Koh, Yung-Hua

Extracellular signal-regulated kinase 1/2 and c-Jun NH2-terminal kinase, through nuclear factor-kappaB and activator protein-1, contribute to caerulein-induced expression of substance P and neurokinin-1 receptors in pancreatic acinar cells. [electronic resource] - The Journal of pharmacology and experimental therapeutics Mar 2010 - 940-8 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1521-0103

10.1124/jpet.109.160416 doi


Acute Disease
Animals
Ceruletide--pharmacology
JNK Mitogen-Activated Protein Kinases--antagonists & inhibitors
Male
Mice
Mitogen-Activated Protein Kinase 1--antagonists & inhibitors
Mitogen-Activated Protein Kinase 3--antagonists & inhibitors
NF-kappa B--physiology
Pancreas--cytology
Pancreatitis--metabolism
Phosphorylation
Protein Precursors--biosynthesis
Receptor, Cholecystokinin A--physiology
Receptors, Neurokinin-1--biosynthesis
Signal Transduction
Substance P--biosynthesis
Tachykinins--biosynthesis
Transcription Factor AP-1--physiology