Leytin, Valery <br/><br/>
The GPIIbIIIa antagonist drugs eptifibatide and tirofiban do not induce activation of apoptosis executioner caspase-3 in resting platelets but inhibit caspase-3 activation in platelets stimulated with thrombin or calcium ionophore A23187.  [electronic resource] 

 -  Haematologica  Dec 2009 
 - 1783-4 p.  digital 
<br/><br/> Publication Type: Letter; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1592-8721 
<br/><br/><label>Standard No.: </label>10.3324/haematol.2009.012708  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Apoptosis--drug effects<br/>Blood Platelets--cytology<br/>Calcimycin--pharmacology<br/>Caspase 3--metabolism<br/>Coagulants--pharmacology<br/>Enzyme Activation--drug effects<br/>Eptifibatide<br/>Flow Cytometry<br/>Humans<br/>Ionophores--pharmacology<br/>Peptides--pharmacology<br/>Platelet Aggregation Inhibitors--pharmacology<br/>Platelet Glycoprotein GPIIb-IIIa Complex--antagonists & inhibitors<br/>Thrombin--pharmacology<br/>Tirofiban<br/>Tyrosine--analogs & derivatives