Huang-Lian-Jie-Du-Tang exerts anti-inflammatory effects in rats through inhibition of nitric oxide production and eicosanoid biosynthesis via the lipoxygenase pathway. [electronic resource]
- The Journal of pharmacy and pharmacology Dec 2009
- 1699-707 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
2042-7158
10.1211/jpp/61.12.0016 doi
Animals Anti-Inflammatory Agents--administration & dosage Calcimycin Carrageenan Cell Line Chemotactic Factors--antagonists & inhibitors Chromatography, High Pressure Liquid Drugs, Chinese Herbal--administration & dosage Eicosanoids--biosynthesis Inflammation--drug therapy Leukotriene B4--biosynthesis Lipopolysaccharides Lipoxygenase--metabolism Macrophages--drug effects Metabolic Networks and Pathways--drug effects Models, Animal Nitric Oxide--biosynthesis Nitric Oxide Synthase Type II--antagonists & inhibitors Phytotherapy Prostaglandin-Endoperoxide Synthases--metabolism RNA, Messenger--metabolism Rats Rats, Sprague-Dawley Receptors, Eicosanoid--metabolism Tandem Mass Spectrometry