A 1,8-naphthyridone derivative targets the HIV-1 Tat-mediated transcription and potently inhibits the HIV-1 replication. [electronic resource]
- Journal of medicinal chemistry Jan 2010
- 641-8 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1520-4804
10.1021/jm901211d doi
Anti-HIV Agents--chemical synthesis Cell Line Drug Delivery Systems--methods Drug Resistance, Viral HIV Infections--drug therapy HIV-1--drug effects HIV-2--drug effects Humans Naphthyridines--chemical synthesis Transcription, Genetic--drug effects Virus Replication--drug effects tat Gene Products, Human Immunodeficiency Virus--genetics