The tumor suppressor p53 transcriptionally regulates cGKI expression during neuronal maturation and is required for cGMP-dependent growth cone collapse. [electronic resource]
- The Journal of neuroscience : the official journal of the Society for Neuroscience Dec 2009
- 15155-60 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1529-2401
10.1523/JNEUROSCI.4416-09.2009 doi
Animals Animals, Newborn Cells, Cultured Cerebral Cortex--cytology Chlorocebus aethiops Chromatin Immunoprecipitation--methods Cyclic GMP--analogs & derivatives Cyclic GMP-Dependent Protein Kinase Type I Cyclic GMP-Dependent Protein Kinases--deficiency Embryo, Mammalian Ganglia, Spinal--cytology Gene Expression Regulation, Developmental--drug effects Green Fluorescent Proteins--genetics Growth Cones--drug effects Mice Mice, Inbred C57BL Mice, Knockout Mutation--genetics Neurons--cytology Organ Culture Techniques RNA, Messenger--metabolism Rats Semaphorin-3A--genetics Transfection--methods Tumor Suppressor Protein p53--deficiency