TY - GEN AU - Chervin,Adam S AU - Stone,Jennifer D AU - Bowerman,Natalie A AU - Kranz,David M TI - Cutting edge: inhibitory effects of CD4 and CD8 on T cell activation induced by high-affinity noncognate ligands SN - 1550-6606 PY - 2010///0212 KW - Animals KW - Antigen Presentation KW - CD4 Antigens KW - metabolism KW - CD8 Antigens KW - Cells, Cultured KW - H-2 Antigens KW - immunology KW - Hybridomas KW - Immune Tolerance KW - Immunosuppressive Agents KW - Ligands KW - Lymphocyte Activation KW - Lymphocyte Specific Protein Tyrosine Kinase p56(lck) KW - Mice KW - Mice, Inbred C57BL KW - Protein Binding KW - Receptors, Antigen, T-Cell KW - antagonists & inhibitors KW - T-Lymphocyte Subsets KW - enzymology N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.4049/jimmunol.0901664 ER -