TY  - GEN
AU  - van Waterschoot,Robert A B
AU  - Lagas,Jurjen S
AU  - Wagenaar,Els
AU  - van der Kruijssen,Cornelia M M
AU  - van Herwaarden,Antonius E
AU  - Song,Ji-Ying
AU  - Rooswinkel,Rogier W
AU  - van Tellingen,Olaf
AU  - Rosing,Hilde
AU  - Beijnen,Jos H
AU  - Schinkel,Alfred H
TI  - Absence of both cytochrome P450 3A and P-glycoprotein dramatically increases docetaxel oral bioavailability and risk of intestinal toxicity
SN  - 1538-7445
PY  - 2009///1221
KW  - ATP Binding Cassette Transporter, Subfamily B, Member 1
KW  - deficiency
KW  - Administration, Oral
KW  - Animals
KW  - Antineoplastic Agents
KW  - blood
KW  - Biological Availability
KW  - Cytochrome P-450 CYP3A
KW  - Docetaxel
KW  - Intestinal Diseases
KW  - Male
KW  - Mice
KW  - Mice, Knockout
KW  - Taxoids
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1158/0008-5472.CAN-09-2915
ER  -