van Waterschoot, Robert A B <br/><br/>
Absence of both cytochrome P450 3A and P-glycoprotein dramatically increases docetaxel oral bioavailability and risk of intestinal toxicity.  [electronic resource] 

 -  Cancer research  Dec 2009 
 - 8996-9002 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1538-7445 
<br/><br/><label>Standard No.: </label>10.1158/0008-5472.CAN-09-2915  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>ATP Binding Cassette Transporter, Subfamily B, Member 1--deficiency<br/>Administration, Oral<br/>Animals<br/>Antineoplastic Agents--blood<br/>Biological Availability<br/>Cytochrome P-450 CYP3A--deficiency<br/>Docetaxel<br/>Intestinal Diseases--blood<br/>Male<br/>Mice<br/>Mice, Knockout<br/>Taxoids--blood