Argiriadi, Maria A

2,4-Diaminopyrimidine MK2 inhibitors. Part I: Observation of an unexpected inhibitor binding mode. [electronic resource] - Bioorganic & medicinal chemistry letters Jan 2010 - 330-3 p. digital

Publication Type: Journal Article

1464-3405

10.1016/j.bmcl.2009.10.102 doi


Adenosine Triphosphate--chemistry
Anti-Inflammatory Agents--chemical synthesis
Binding Sites
Binding, Competitive
Computer Simulation
Intracellular Signaling Peptides and Proteins--antagonists & inhibitors
Protein Kinase Inhibitors--chemical synthesis
Protein Serine-Threonine Kinases--antagonists & inhibitors
Pyrimidines--chemical synthesis
Structure-Activity Relationship