TY - GEN AU - Fannin,Rick D AU - Russo,Mark AU - O'Connell,Thomas M AU - Gerrish,Kevin AU - Winnike,Jason H AU - Macdonald,Jeffrey AU - Newton,Jack AU - Malik,Shahid AU - Sieber,Stella O AU - Parker,Joel AU - Shah,Ruchir AU - Zhou,Tong AU - Watkins,Paul B AU - Paules,Richard S TI - Acetaminophen dosing of humans results in blood transcriptome and metabolome changes consistent with impaired oxidative phosphorylation SN - 1527-3350 PY - 2010///0115 KW - Acetaminophen KW - adverse effects KW - Adult KW - Animals KW - Biomarkers KW - blood KW - Chemical and Drug Induced Liver Injury KW - diagnosis KW - Down-Regulation KW - Gene Expression Profiling KW - Humans KW - Liver KW - metabolism KW - Metabolome KW - drug effects KW - Middle Aged KW - Oxidative Phosphorylation KW - Placebos KW - Rats N1 - Publication Type: Controlled Clinical Trial; Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1002/hep.23330 ER -