TY - GEN AU - Karreth,Florian A AU - DeNicola,Gina M AU - Winter,Stephen P AU - Tuveson,David A TI - C-Raf inhibits MAPK activation and transformation by B-Raf(V600E) SN - 1097-4164 PY - 2010///0106 KW - Animals KW - Benzenesulfonates KW - pharmacology KW - Blotting, Western KW - Cell Line KW - Cell Line, Tumor KW - Cell Proliferation KW - Cell Transformation, Neoplastic KW - genetics KW - Enzyme Activation KW - Humans KW - Immunoprecipitation KW - MAP Kinase Signaling System KW - Melanoma KW - Mice KW - Mitogen-Activated Protein Kinases KW - metabolism KW - Mutation KW - NIH 3T3 Cells KW - Niacinamide KW - analogs & derivatives KW - Phenylurea Compounds KW - Phosphorylation KW - Protein Binding KW - drug effects KW - Protein Kinase Inhibitors KW - Proto-Oncogene Mas KW - Proto-Oncogene Proteins B-raf KW - Proto-Oncogene Proteins c-raf KW - Pyridines KW - Sorafenib KW - Transfection KW - ras Proteins N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.molcel.2009.10.017 ER -