Hou, Weihong

Zinc mesoporphyrin induces rapid proteasomal degradation of hepatitis C nonstructural 5A protein in human hepatoma cells. [electronic resource] - Gastroenterology May 2010 - 1909-19 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1528-0012

10.1053/j.gastro.2009.11.001 doi


Antiviral Agents--pharmacology
Carcinoma, Hepatocellular--genetics
Cell Line, Tumor
Cysteine Proteinase Inhibitors--pharmacology
Dose-Response Relationship, Drug
Down-Regulation
Half-Life
Hepacivirus--drug effects
Humans
Leupeptins--pharmacology
Liver Neoplasms--genetics
Metalloporphyrins--pharmacology
Oligopeptides--pharmacology
Proteasome Endopeptidase Complex--drug effects
Protein Processing, Post-Translational--drug effects
Protein Stability
RNA, Viral--biosynthesis
Time Factors
Transfection
Ubiquitination
Viral Nonstructural Proteins--genetics
Virus Replication--drug effects