TY  - GEN
AU  - Amritraj,Asha
AU  - Peake,Kyle
AU  - Kodam,Anitha
AU  - Salio,Chiara
AU  - Merighi,Adalberto
AU  - Vance,Jean E
AU  - Kar,Satyabrata
TI  - Increased activity and altered subcellular distribution of lysosomal enzymes determine neuronal vulnerability in Niemann-Pick type C1-deficient mice
SN  - 1525-2191
PY  - 2010///0225
KW  - Animals
KW  - Cathepsin B
KW  - metabolism
KW  - Cathepsin D
KW  - Cerebellum
KW  - Cholesterol
KW  - Fluorescent Antibody Technique
KW  - Hippocampus
KW  - Immunoblotting
KW  - Intracellular Signaling Peptides and Proteins
KW  - Lysosomes
KW  - enzymology
KW  - Mice
KW  - Mice, Inbred BALB C
KW  - Mice, Knockout
KW  - Microscopy, Electron, Transmission
KW  - Nerve Degeneration
KW  - Neurons
KW  - Niemann-Pick C1 Protein
KW  - Niemann-Pick Disease, Type C
KW  - Proteins
KW  - genetics
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.2353/ajpath.2009.081096
ER  -