Protein kinase Cbeta modulates ligand-induced cell surface death receptor accumulation: a mechanistic basis for enzastaurin-death ligand synergy. [electronic resource]
- The Journal of biological chemistry Jan 2010
- 888-902 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1083-351X
10.1074/jbc.M109.057638 doi
Apoptosis--drug effects Carcinogens--pharmacology Cell Proliferation--drug effects Enzyme Activators--pharmacology Fas Ligand Protein--pharmacology HL-60 Cells Humans Indoles--pharmacology Isoenzymes--antagonists & inhibitors Jurkat Cells Phosphorylation--drug effects Protein Kinase C--antagonists & inhibitors Protein Kinase C beta Protein Transport--drug effects Receptors, TNF-Related Apoptosis-Inducing Ligand--metabolism Signal Transduction--drug effects Tetradecanoylphorbol Acetate--pharmacology Tumor Necrosis Factor-alpha--pharmacology fas Receptor--metabolism