TY  - GEN
AU  - Srinivasan,Balasubramanian
AU  - Johnson,Thomas E
AU  - Lad,Rahul
AU  - Xing,Chengguo
TI  - Structure-activity relationship studies of chalcone leading to 3-hydroxy-4,3',4',5'-tetramethoxychalcone and its analogues as potent nuclear factor kappaB inhibitors and their anticancer activities
SN  - 1520-4804
PY  - 2009///1221
KW  - Animals
KW  - Antineoplastic Agents
KW  - chemistry
KW  - Cell Line, Tumor
KW  - Cell Proliferation
KW  - drug effects
KW  - Cell Transformation, Neoplastic
KW  - Chalcone
KW  - analogs & derivatives
KW  - Chalcones
KW  - Female
KW  - Genes, Reporter
KW  - Humans
KW  - I-kappa B Kinase
KW  - antagonists & inhibitors
KW  - Inhibitory Concentration 50
KW  - Interleukin-1 Receptor-Associated Kinases
KW  - Luciferases
KW  - metabolism
KW  - Lung Neoplasms
KW  - drug therapy
KW  - Mice
KW  - Mice, Nude
KW  - NF-kappa B
KW  - Structure-Activity Relationship
KW  - Tumor Necrosis Factor-alpha
KW  - pharmacology
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1021/jm901278z
ER  -