Srinivasan, Balasubramanian <br/><br/>
Structure-activity relationship studies of chalcone leading to 3-hydroxy-4,3',4',5'-tetramethoxychalcone and its analogues as potent nuclear factor kappaB inhibitors and their anticancer activities.  [electronic resource] 

 -  Journal of medicinal chemistry  Nov 2009 
 - 7228-35 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1520-4804 
<br/><br/><label>Standard No.: </label>10.1021/jm901278z  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Antineoplastic Agents--chemistry<br/>Cell Line, Tumor<br/>Cell Proliferation--drug effects<br/>Cell Transformation, Neoplastic<br/>Chalcone--analogs & derivatives<br/>Chalcones--chemistry<br/>Female<br/>Genes, Reporter<br/>Humans<br/>I-kappa B Kinase--antagonists & inhibitors<br/>Inhibitory Concentration 50<br/>Interleukin-1 Receptor-Associated Kinases--antagonists & inhibitors<br/>Luciferases--metabolism<br/>Lung Neoplasms--drug therapy<br/>Mice<br/>Mice, Nude<br/>NF-kappa B--antagonists & inhibitors<br/>Structure-Activity Relationship<br/>Tumor Necrosis Factor-alpha--pharmacology