TY  - GEN
AU  - Khrapunovich-Baine,Marina
AU  - Menon,Vilas
AU  - Verdier-Pinard,Pascal
AU  - Smith,Amos B
AU  - Angeletti,Ruth Hogue
AU  - Fiser,Andras
AU  - Horwitz,Susan Band
AU  - Xiao,Hui
TI  - Distinct pose of discodermolide in taxol binding pocket drives a complementary mode of microtubule stabilization
SN  - 1520-4995
PY  - 2010///0112
KW  - Alkanes
KW  - chemistry
KW  - Animals
KW  - Binding Sites
KW  - drug effects
KW  - Carbamates
KW  - Cattle
KW  - Chickens
KW  - Deuterium Exchange Measurement
KW  - Dimerization
KW  - Drug Synergism
KW  - Lactones
KW  - Microtubules
KW  - Paclitaxel
KW  - Peptide Fragments
KW  - blood
KW  - Protein Binding
KW  - Protein Isoforms
KW  - Protein Stability
KW  - Pyrones
KW  - Tubulin
KW  - Tubulin Modulators
N1  - Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1021/bi901351q
ER  -