TY - GEN AU - Trova,Michael P AU - Barnes,Keith D AU - Barford,Curt AU - Benanti,Travis AU - Bielaska,Mark AU - Burry,Lori AU - Lehman,John M AU - Murphy,Christine AU - O'Grady,Harold AU - Peace,Denise AU - Salamone,Susan AU - Smith,Jennifer AU - Snider,Patricia AU - Toporowski,Joseph AU - Tregay,Steven AU - Wilson,Alison AU - Wyle,Michael AU - Zheng,Xiaozhang AU - Friedrich,Thomas D TI - Biaryl purine derivatives as potent antiproliferative agents: inhibitors of cyclin dependent kinases. Part I SN - 1464-3405 PY - 2010///0119 KW - Antineoplastic Agents KW - chemical synthesis KW - Cell Proliferation KW - drug effects KW - Cyclin-Dependent Kinases KW - antagonists & inhibitors KW - Drug Design KW - Drug Screening Assays, Antitumor KW - HeLa Cells KW - Humans KW - Molecular Structure KW - Protein Kinase Inhibitors KW - Purines KW - Roscovitine KW - Stereoisomerism KW - Structure-Activity Relationship N1 - Publication Type: Journal Article UR - https://doi.org/10.1016/j.bmcl.2009.10.025 ER -