TY - GEN AU - Honsho,Shoken AU - Nishikawa,Susumu AU - Amano,Katsuya AU - Zen,Kan AU - Adachi,Yasushi AU - Kishita,Eigo AU - Matsui,Akihiro AU - Katsume,Asako AU - Yamaguchi,Shinichiro AU - Nishikawa,Kenichiro AU - Isoda,Kikuo AU - Riches,David W H AU - Matoba,Satoaki AU - Okigaki,Mitsuhiko AU - Matsubara,Hiroaki TI - Pressure-mediated hypertrophy and mechanical stretch induces IL-1 release and subsequent IGF-1 generation to maintain compensative hypertrophy by affecting Akt and JNK pathways SN - 1524-4571 PY - 2009///1217 KW - Animals KW - Apoptosis KW - physiology KW - Endomyocardial Fibrosis KW - metabolism KW - Extracellular Signal-Regulated MAP Kinases KW - Hypertrophy, Left Ventricular KW - Insulin-Like Growth Factor I KW - Interleukin-1beta KW - genetics KW - JNK Mitogen-Activated Protein Kinases KW - Janus Kinase 2 KW - Mice KW - Mice, Mutant Strains KW - Myocytes, Cardiac KW - Proto-Oncogene Proteins c-akt KW - Reactive Oxygen Species KW - Receptors, Interleukin-1 KW - STAT5 Transcription Factor KW - Signal Transduction KW - Stress, Mechanical KW - Ventricular Pressure N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1161/CIRCRESAHA.109.208199 ER -