Massonnet, Benoit <br/><br/>
Pharmacological inhibitors of the mevalonate pathway activate pro-IL-1 processing and IL-1 release by human monocytes.  [electronic resource] 

 -  European cytokine network  Sep 2009 
 - 112-20 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1952-4005 
<br/><br/><label>Standard No.: </label>10.1684/ecn.2009.0162  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Caspase 1--metabolism<br/>Cell Line<br/>Enzyme Activation--drug effects<br/>Guanosine Triphosphate--metabolism<br/>Humans<br/>Hydroxymethylglutaryl-CoA Reductase Inhibitors--pharmacology<br/>Interleukin-1--metabolism<br/>Interleukin-1beta--metabolism<br/>Lipopolysaccharides--pharmacology<br/>Metabolic Networks and Pathways--drug effects<br/>Mevalonic Acid--metabolism<br/>Monocytes--drug effects<br/>Phosphorylation--drug effects<br/>Protein Precursors--metabolism<br/>Protein Prenylation--drug effects<br/>Protein Processing, Post-Translational--drug effects<br/>Protein Transport--drug effects<br/>Simvastatin--pharmacology<br/>p38 Mitogen-Activated Protein Kinases--metabolism<br/>rac1 GTP-Binding Protein--metabolism