Sala Frigerio, Carlo <br/><br/>
An NSAID-like compound, FT-9, preferentially inhibits gamma-secretase cleavage of the amyloid precursor protein compared to its effect on amyloid precursor-like protein 1.  [electronic resource] 

 -  Biochemistry  Nov 2009 
 - 10894-904 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1520-4995 
<br/><br/><label>Standard No.: </label>10.1021/bi901237k  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Amyloid Precursor Protein Secretases--antagonists & inhibitors<br/>Amyloid beta-Peptides--metabolism<br/>Amyloid beta-Protein Precursor--metabolism<br/>Animals<br/>Anti-Inflammatory Agents, Non-Steroidal--pharmacology<br/>Benzodiazepinones--pharmacology<br/>Biocatalysis--drug effects<br/>CHO Cells<br/>Cricetinae<br/>Cricetulus<br/>Dipeptides--pharmacology<br/>Fenofibrate--analogs & derivatives<br/>Flurbiprofen--pharmacology<br/>Humans<br/>Kinetics<br/>Microsomes--drug effects<br/>Nerve Tissue Proteins--metabolism<br/>Peptide Fragments--metabolism<br/>Protease Inhibitors--pharmacology<br/>Recombinant Proteins--genetics<br/>Substrate Specificity--drug effects<br/>Transfection