The NRG1 gene is frequently silenced by methylation in breast cancers and is a strong candidate for the 8p tumour suppressor gene. [electronic resource]
- Oncogene Nov 2009
- 4041-52 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1476-5594
10.1038/onc.2009.259 doi
Base Sequence Breast Neoplasms--genetics Cell Line, Tumor Cell Proliferation Chromosome Aberrations Chromosome Mapping Chromosomes, Human, Pair 8--chemistry CpG Islands--genetics DNA Methylation Female Gene Expression Regulation, Neoplastic Gene Silencing Genes, Tumor Suppressor Genetic Predisposition to Disease--genetics Humans Neuregulin-1--genetics Transcription Initiation Site