TY - GEN AU - Zhou,Jinming AU - Liu,Bing AU - Geng,Guoyan AU - Wu,Jian Hui TI - Study of the impact of the T877A mutation on ligand-induced helix-12 positioning of the androgen receptor resulted in design and synthesis of novel antiandrogens SN - 1097-0134 PY - 2010///0325 KW - Androgen Antagonists KW - chemical synthesis KW - Androgen Receptor Antagonists KW - Binding Sites KW - Cluster Analysis KW - Drug Design KW - Flutamide KW - analogs & derivatives KW - Ligands KW - Molecular Dynamics Simulation KW - Mutation KW - Principal Component Analysis KW - Protein Interaction Domains and Motifs KW - Receptors, Androgen KW - chemistry N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1002/prot.22592 ER -