Synergism of hydroxyapatite nanoparticles and recombinant mutant human tumour necrosis factor-alpha in chemotherapy of multidrug-resistant hepatocellular carcinoma. [electronic resource]
- Liver international : official journal of the International Association for the Study of the Liver Apr 2010
- 585-92 p. digital
Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
1478-3231
10.1111/j.1478-3231.2009.02113.x doi
Animals Antineoplastic Combined Chemotherapy Protocols--adverse effects Apoptosis--drug effects Blotting, Western Carcinoma, Hepatocellular--drug therapy Cell Line, Tumor Cell Proliferation--drug effects Disease Models, Animal Dose-Response Relationship, Drug Drug Administration Schedule Drug Resistance, Multiple Drug Resistance, Neoplasm Drug Synergism Durapatite--pharmacology Female Genes, MDR--drug effects Humans Liver Neoplasms--drug therapy Mice Mice, Inbred BALB C Multidrug Resistance-Associated Proteins--drug effects Neoplasms, Experimental--drug therapy Probability RNA, Messenger--metabolism Random Allocation Reverse Transcriptase Polymerase Chain Reaction Tumor Necrosis Factor-alpha--pharmacology