Atack, John R <br/><br/>
Benzodiazepine binding site occupancy by the novel GABAA receptor subtype-selective drug 7-(1,1-dimethylethyl)-6-(2-ethyl-2H-1,2,4-triazol-3-ylmethoxy)-3-(2-fluorophenyl)-1,2,4-triazolo[4,3-b]pyridazine (TPA023) in rats, primates, and humans.  [electronic resource] 

 -  The Journal of pharmacology and experimental therapeutics  Jan 2010 
 - 17-25 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1521-0103 
<br/><br/><label>Standard No.: </label>10.1124/jpet.109.157909  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Binding Sites<br/>Brain--drug effects<br/>Dose-Response Relationship, Drug<br/>Flumazenil--pharmacology<br/>GABA Agonists--blood<br/>GABA-A Receptor Agonists<br/>GABA-A Receptor Antagonists<br/>Humans<br/>Macaca mulatta<br/>Papio<br/>Positron-Emission Tomography<br/>Protein Binding<br/>Protein Subunits<br/>Pyridazines--blood<br/>Radioligand Assay<br/>Rats<br/>Species Specificity<br/>Tissue Distribution<br/>Triazoles--blood