TY  - GEN
AU  - Roy Choudhury,Subhasree
AU  - Karmakar,Surajit
AU  - Banik,Naren L
AU  - Ray,Swapan K
TI  - Synergistic efficacy of sorafenib and genistein in growth inhibition by down regulating angiogenic and survival factors and increasing apoptosis through upregulation of p53 and p21 in malignant neuroblastoma cells having N-Myc amplification or non-amplification
SN  - 1573-0646
PY  - 2011///0203
KW  - Angiogenesis Inducing Agents
KW  - metabolism
KW  - Apoptosis
KW  - drug effects
KW  - Benzenesulfonates
KW  - pharmacology
KW  - Caspase 3
KW  - Cell Cycle
KW  - Cell Proliferation
KW  - Cell Shape
KW  - Cell Survival
KW  - Cyclin-Dependent Kinase Inhibitor p21
KW  - Down-Regulation
KW  - Drug Synergism
KW  - Flow Cytometry
KW  - Gene Amplification
KW  - Genistein
KW  - Humans
KW  - Mitochondria
KW  - Myeloid Cell Leukemia Sequence 1 Protein
KW  - Neuroblastoma
KW  - drug therapy
KW  - Niacinamide
KW  - analogs & derivatives
KW  - Phenylurea Compounds
KW  - Proto-Oncogene Proteins c-bcl-2
KW  - Proto-Oncogene Proteins c-myc
KW  - genetics
KW  - Pyridines
KW  - Signal Transduction
KW  - Sorafenib
KW  - Telomerase
KW  - Treatment Outcome
KW  - Tumor Suppressor Protein p53
KW  - Up-Regulation
KW  - bcl-2-Associated X Protein
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural
UR  - https://doi.org/10.1007/s10637-009-9324-7
ER  -