Momeny, Majid <br/><br/>
Arsenic trioxide induces apoptosis in NB-4, an acute promyelocytic leukemia cell line, through up-regulation of p73 via suppression of nuclear factor kappa B-mediated inhibition of p73 transcription and prevention of NF-kappaB-mediated induction of XIAP, cIAP2, BCL-XL and survivin.  [electronic resource] 

 -  Medical oncology (Northwood, London, England)  Sep 2010 
 - 833-42 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1559-131X 
<br/><br/><label>Standard No.: </label>10.1007/s12032-009-9294-9  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Acute-Phase Proteins--biosynthesis<br/>Apoptosis--drug effects<br/>Arsenic Trioxide<br/>Arsenicals--pharmacology<br/>Ataxia Telangiectasia Mutated Proteins<br/>Baculoviral IAP Repeat-Containing 3 Protein<br/>Carrier Proteins--biosynthesis<br/>Caspase 3--biosynthesis<br/>Cell Cycle Proteins--biosynthesis<br/>Cell Line, Tumor--drug effects<br/>Cyclin-Dependent Kinase Inhibitor p21--biosynthesis<br/>DNA-Binding Proteins--biosynthesis<br/>Gene Expression Regulation, Neoplastic--drug effects<br/>Heat-Shock Proteins--biosynthesis<br/>Histone Acetyltransferases--biosynthesis<br/>Humans<br/>I-kappa B Kinase--biosynthesis<br/>Inhibitor of Apoptosis Proteins--biosynthesis<br/>Lipocalin-2<br/>Lipocalins--biosynthesis<br/>Lysine Acetyltransferase 5<br/>Microtubule-Associated Proteins--biosynthesis<br/>NF-kappa B--antagonists & inhibitors<br/>Neoplasm Proteins--biosynthesis<br/>Nuclear Proteins--biosynthesis<br/>Oxides--pharmacology<br/>Protein Serine-Threonine Kinases--biosynthesis<br/>Protein Tyrosine Phosphatase, Non-Receptor Type 11--biosynthesis<br/>Proto-Oncogene Proteins--biosynthesis<br/>RNA, Messenger--biosynthesis<br/>RNA, Neoplasm--biosynthesis<br/>Sirtuin 1--biosynthesis<br/>Survivin<br/>Transcription, Genetic--drug effects<br/>Tumor Protein p73<br/>Tumor Suppressor Proteins--biosynthesis<br/>Ubiquitin-Protein Ligases<br/>X-Linked Inhibitor of Apoptosis Protein--biosynthesis<br/>bcl-X Protein--biosynthesis