Chen, Shuzhen

Ischemia-induced brain damage is enhanced in human renin and angiotensinogen double-transgenic mice. [electronic resource] - American journal of physiology. Regulatory, integrative and comparative physiology Nov 2009 - R1526-31 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1522-1490

10.1152/ajpregu.91040.2008 doi


Angiotensin II--metabolism
Angiotensin II Type 1 Receptor Blockers--pharmacology
Angiotensinogen--genetics
Animals
Blood Pressure--physiology
Brain--blood supply
Brain Ischemia--etiology
Cell Death--physiology
Disease Models, Animal
Humans
Infarction, Middle Cerebral Artery--complications
Losartan--pharmacology
Male
Mice
Mice, Transgenic
Receptor, Angiotensin, Type 1--drug effects
Regional Blood Flow--physiology
Renin--genetics
Severity of Illness Index
Signal Transduction--physiology