Ischemia-induced brain damage is enhanced in human renin and angiotensinogen double-transgenic mice. [electronic resource]
- American journal of physiology. Regulatory, integrative and comparative physiology Nov 2009
- R1526-31 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1522-1490
10.1152/ajpregu.91040.2008 doi
Angiotensin II--metabolism Angiotensin II Type 1 Receptor Blockers--pharmacology Angiotensinogen--genetics Animals Blood Pressure--physiology Brain--blood supply Brain Ischemia--etiology Cell Death--physiology Disease Models, Animal Humans Infarction, Middle Cerebral Artery--complications Losartan--pharmacology Male Mice Mice, Transgenic Receptor, Angiotensin, Type 1--drug effects Regional Blood Flow--physiology Renin--genetics Severity of Illness Index Signal Transduction--physiology