TY - GEN AU - Ernst,Marianne B AU - Wunderlich,Claudia M AU - Hess,Simon AU - Paehler,Moritz AU - Mesaros,Andrea AU - Koralov,Sergei B AU - Kleinridders,André AU - Husch,Andreas AU - Münzberg,Heike AU - Hampel,Brigitte AU - Alber,Jens AU - Kloppenburg,Peter AU - Brüning,Jens C AU - Wunderlich,F Thomas TI - Enhanced Stat3 activation in POMC neurons provokes negative feedback inhibition of leptin and insulin signaling in obesity SN - 1529-2401 PY - 2009///1002 KW - Agouti-Related Protein KW - genetics KW - Animals KW - Body Composition KW - Body Weight KW - Disease Models, Animal KW - Eating KW - Electrophoretic Mobility Shift Assay KW - Enzyme-Linked Immunosorbent Assay KW - methods KW - Feedback KW - physiology KW - Gene Expression Regulation KW - drug effects KW - Glucose Tolerance Test KW - Green Fluorescent Proteins KW - Hypothalamus KW - pathology KW - In Vitro Techniques KW - Insulin KW - metabolism KW - Insulin Resistance KW - Leptin KW - Leukemia Inhibitory Factor KW - pharmacology KW - Membrane Proteins KW - Mice KW - Mice, Transgenic KW - Neural Inhibition KW - Neurons KW - Neuropeptide Y KW - Obesity KW - Patch-Clamp Techniques KW - Phosphatidylinositol 3-Kinases KW - Pro-Opiomelanocortin KW - Signal Transduction KW - Suppressor of Cytokine Signaling 3 Protein KW - Suppressor of Cytokine Signaling Proteins KW - Transfection N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1523/JNEUROSCI.5712-08.2009 ER -