Subramani, Jaganathan
Atorvastatin restores the impaired vascular endothelium-dependent relaxations mediated by nitric oxide and endothelium-derived hyperpolarizing factors but not hypotension in sepsis. [electronic resource]
- Journal of cardiovascular pharmacology Dec 2009
- 526-34 p. digital
Publication Type: Journal Article
ISSN: 1533-4023
Standard No.: 10.1097/FJC.0b013e3181bfafd6 doi
Subjects--Topical Terms: Acetylcholine--pharmacology Animals Aorta--drug effects Atorvastatin Biological Factors--antagonists & inhibitors Blood Cell Count Blood Pressure--drug effects Calcium Channel Blockers--pharmacology Cytochrome P-450 Enzyme Inhibitors Disease Models, Animal Endothelium, Vascular--drug effects Gene Expression--drug effects Heptanoic Acids--pharmacology Hydroxymethylglutaryl-CoA Reductase Inhibitors--pharmacology Hypotension--etiology Indomethacin--pharmacology Male NG-Nitroarginine Methyl Ester--pharmacology Nitric Oxide--antagonists & inhibitors Nitric Oxide Synthase Type II--antagonists & inhibitors Nitric Oxide Synthase Type III--antagonists & inhibitors Nitrites--blood Nitroprusside--pharmacology Phenylephrine--pharmacology Pulmonary Artery--drug effects Pyrroles--pharmacology Rats Rats, Wistar Sepsis--blood Vasodilation--drug effects