Subramani, Jaganathan

Atorvastatin restores the impaired vascular endothelium-dependent relaxations mediated by nitric oxide and endothelium-derived hyperpolarizing factors but not hypotension in sepsis. [electronic resource] - Journal of cardiovascular pharmacology Dec 2009 - 526-34 p. digital

Publication Type: Journal Article

1533-4023

10.1097/FJC.0b013e3181bfafd6 doi


Acetylcholine--pharmacology
Animals
Aorta--drug effects
Atorvastatin
Biological Factors--antagonists & inhibitors
Blood Cell Count
Blood Pressure--drug effects
Calcium Channel Blockers--pharmacology
Cytochrome P-450 Enzyme Inhibitors
Disease Models, Animal
Endothelium, Vascular--drug effects
Gene Expression--drug effects
Heptanoic Acids--pharmacology
Hydroxymethylglutaryl-CoA Reductase Inhibitors--pharmacology
Hypotension--etiology
Indomethacin--pharmacology
Male
NG-Nitroarginine Methyl Ester--pharmacology
Nitric Oxide--antagonists & inhibitors
Nitric Oxide Synthase Type II--antagonists & inhibitors
Nitric Oxide Synthase Type III--antagonists & inhibitors
Nitrites--blood
Nitroprusside--pharmacology
Phenylephrine--pharmacology
Pulmonary Artery--drug effects
Pyrroles--pharmacology
Rats
Rats, Wistar
Sepsis--blood
Vasodilation--drug effects