TY - GEN AU - Hohla,Florian AU - Buchholz,Stefan AU - Schally,Andrew V AU - Seitz,Stefan AU - Rick,Ferenc G AU - Szalontay,Luca AU - Varga,Jozsef L AU - Zarandi,Marta AU - Halmos,Gabor AU - Vidaurre,Irving AU - Krishan,Awtar AU - Kurtoglu,Metin AU - Chandna,Sudhir AU - Aigner,Elmar AU - Datz,Christian TI - GHRH antagonist causes DNA damage leading to p21 mediated cell cycle arrest and apoptosis in human colon cancer cells SN - 1551-4005 PY - 2010///0114 KW - Animals KW - Apoptosis KW - Caspase 3 KW - metabolism KW - Caspase 9 KW - Cell Line, Tumor KW - Colonic Neoplasms KW - drug therapy KW - Cyclin-Dependent Kinase Inhibitor p21 KW - DNA Damage KW - DNA Fragmentation KW - drug effects KW - Growth Hormone-Releasing Hormone KW - antagonists & inhibitors KW - HCT116 Cells KW - Humans KW - Male KW - Membrane Potential, Mitochondrial KW - physiology KW - Mice KW - Mice, Nude KW - Poly(ADP-ribose) Polymerases KW - Proto-Oncogene Proteins c-bcl-2 KW - S Phase KW - Sermorelin KW - analogs & derivatives KW - Transplantation, Heterologous KW - Tumor Suppressor Protein p53 KW - bcl-2-Associated X Protein N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S UR - https://doi.org/10.4161/cc.8.19.9698 ER -