Hohla, Florian <br/><br/>
GHRH antagonist causes DNA damage leading to p21 mediated cell cycle arrest and apoptosis in human colon cancer cells.  [electronic resource] 

 -  Cell cycle (Georgetown, Tex.)  Oct 2009 
 - 3149-56 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. 
<br/><br/><label>ISSN: </label>1551-4005 
<br/><br/><label>Standard No.: </label>10.4161/cc.8.19.9698  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Apoptosis<br/>Caspase 3--metabolism<br/>Caspase 9--metabolism<br/>Cell Line, Tumor<br/>Colonic Neoplasms--drug therapy<br/>Cyclin-Dependent Kinase Inhibitor p21--metabolism<br/>DNA Damage<br/>DNA Fragmentation--drug effects<br/>Growth Hormone-Releasing Hormone--antagonists & inhibitors<br/>HCT116 Cells<br/>Humans<br/>Male<br/>Membrane Potential, Mitochondrial--physiology<br/>Mice<br/>Mice, Nude<br/>Poly(ADP-ribose) Polymerases--metabolism<br/>Proto-Oncogene Proteins c-bcl-2--metabolism<br/>S Phase<br/>Sermorelin--analogs & derivatives<br/>Transplantation, Heterologous<br/>Tumor Suppressor Protein p53--metabolism<br/>bcl-2-Associated X Protein--metabolism