TY - GEN AU - Hawkins,Nicholas J AU - Lee,James H-F AU - Wong,Justin J-L AU - Kwok,Chau-To AU - Ward,Robyn L AU - Hitchins,Megan P TI - MGMT methylation is associated primarily with the germline C>T SNP (rs16906252) in colorectal cancer and normal colonic mucosa SN - 1530-0285 PY - 2010///0128 KW - Adult KW - Aged KW - Aged, 80 and over KW - Australia KW - Carcinoma KW - enzymology KW - Chromosomes, Human, Pair 10 KW - Colorectal Neoplasms KW - Cyclin-Dependent Kinase Inhibitor p16 KW - genetics KW - DNA Methylation KW - DNA Modification Methylases KW - DNA Repair Enzymes KW - Epigenesis, Genetic KW - Female KW - Gene Expression Regulation, Enzymologic KW - Gene Expression Regulation, Neoplastic KW - Gene Frequency KW - Genetic Predisposition to Disease KW - Germ-Line Mutation KW - Humans KW - Immunohistochemistry KW - Intestinal Mucosa KW - Male KW - Middle Aged KW - Neoplasm Invasiveness KW - Neoplasm Staging KW - Odds Ratio KW - Phenotype KW - Polymerase Chain Reaction KW - Polymorphism, Single Nucleotide KW - Prospective Studies KW - Proto-Oncogene Proteins KW - Proto-Oncogene Proteins p21(ras) KW - Tumor Suppressor Proteins KW - ras Proteins N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/modpathol.2009.130 ER -