Hawkins, Nicholas J

MGMT methylation is associated primarily with the germline C>T SNP (rs16906252) in colorectal cancer and normal colonic mucosa. [electronic resource] - Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc Dec 2009 - 1588-99 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1530-0285

10.1038/modpathol.2009.130 doi


Adult
Aged
Aged, 80 and over
Australia
Carcinoma--enzymology
Chromosomes, Human, Pair 10
Colorectal Neoplasms--enzymology
Cyclin-Dependent Kinase Inhibitor p16--genetics
DNA Methylation
DNA Modification Methylases--genetics
DNA Repair Enzymes--genetics
Epigenesis, Genetic
Female
Gene Expression Regulation, Enzymologic
Gene Expression Regulation, Neoplastic
Gene Frequency
Genetic Predisposition to Disease
Germ-Line Mutation
Humans
Immunohistochemistry
Intestinal Mucosa--enzymology
Male
Middle Aged
Neoplasm Invasiveness
Neoplasm Staging
Odds Ratio
Phenotype
Polymerase Chain Reaction
Polymorphism, Single Nucleotide
Prospective Studies
Proto-Oncogene Proteins--genetics
Proto-Oncogene Proteins p21(ras)
Tumor Suppressor Proteins--genetics
ras Proteins--genetics