TY - GEN AU - Castilho,Rogerio M AU - Squarize,Cristiane H AU - Chodosh,Lewis A AU - Williams,Bart O AU - Gutkind,J Silvio TI - mTOR mediates Wnt-induced epidermal stem cell exhaustion and aging SN - 1875-9777 PY - 2009///1104 KW - Animals KW - Antigens, CD34 KW - metabolism KW - Cell Proliferation KW - drug effects KW - Cell Separation KW - Cellular Senescence KW - Doxycycline KW - pharmacology KW - Epidermal Cells KW - Epithelial Cells KW - cytology KW - Hair Follicle KW - Keratinocytes KW - Mice KW - Protein Kinases KW - Regeneration KW - Signal Transduction KW - Sirolimus KW - Stem Cells KW - TOR Serine-Threonine Kinases KW - Wnt Proteins KW - beta Catenin N1 - Publication Type: Journal Article; Research Support, N.I.H., Intramural UR - https://doi.org/10.1016/j.stem.2009.06.017 ER -