TY - GEN AU - Lang,James A AU - Jennings,John D AU - Holowatz,Lacy A AU - Kenney,W Larry TI - Reflex vasoconstriction in aged human skin increasingly relies on Rho kinase-dependent mechanisms during whole body cooling SN - 1522-1539 PY - 2009///1112 KW - 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine KW - administration & dosage KW - Age Factors KW - Aged KW - Aging KW - physiology KW - Blood Flow Velocity KW - Blood Pressure KW - Blood Vessels KW - enzymology KW - Body Temperature Regulation KW - Cold Temperature KW - Female KW - Forearm KW - Humans KW - Laser-Doppler Flowmetry KW - Male KW - Microdialysis KW - Muscle, Smooth, Vascular KW - drug effects KW - NG-Nitroarginine Methyl Ester KW - Nitric Oxide KW - metabolism KW - Nitric Oxide Donors KW - Nitric Oxide Synthase KW - antagonists & inhibitors KW - Nitroprusside KW - Norepinephrine KW - Protein Kinase Inhibitors KW - Reflex KW - Regional Blood Flow KW - Skin KW - blood supply KW - Vasoconstriction KW - Vasodilator Agents KW - Young Adult KW - rho-Associated Kinases N1 - Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1152/ajpheart.00509.2009 ER -