TY - GEN AU - Giammona,Lisa M AU - Panuganti,Swapna AU - Kemper,Jan M AU - Apostolidis,Pani A AU - Lindsey,Stephan AU - Papoutsakis,Eleftherios T AU - Miller,William M TI - Mechanistic studies on the effects of nicotinamide on megakaryocytic polyploidization and the roles of NAD+ levels and SIRT inhibition SN - 1873-2399 PY - 2009///1123 KW - Acetylation KW - drug effects KW - Aneugens KW - pharmacology KW - Apoptosis KW - Cell Culture Techniques KW - methods KW - Cells, Cultured KW - Consensus Sequence KW - Cytokines KW - DNA KW - metabolism KW - Humans KW - Megakaryocytes KW - NAD KW - physiology KW - Naphthalenes KW - Niacinamide KW - Nucleosomes KW - Polyploidy KW - Protein Binding KW - Protein Processing, Post-Translational KW - Pyrimidinones KW - Sirtuin 1 KW - antagonists & inhibitors KW - Sirtuin 2 KW - Tumor Suppressor Protein p53 N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.exphem.2009.08.004 ER -